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MADD antibody (AA 851-950) (AbBy Fluor® 680)

MADD Reactivity: Mouse IF (p), IF (cc) Host: Rabbit Polyclonal AbBy Fluor® 680
Catalog No. ABIN6943992
  • Target See all MADD Antibodies
    MADD (MAP-Kinase Activating Death Domain (MADD))
    Binding Specificity
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 851-950
    Reactivity
    • 31
    • 23
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 38
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MADD antibody is conjugated to AbBy Fluor® 680
    Application
    • 15
    • 14
    • 12
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DENN
    Isotype
    IgG
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  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MADD (MAP-Kinase Activating Death Domain (MADD))
    Alternative Name
    MADD (MADD Products)
    Synonyms
    MADD antibody, MGC145371 antibody, DENN antibody, IG20 antibody, RAB3GEP antibody, 9630059K23Rik antibody, MAP kinase activating death domain antibody, MAP-kinase activating death domain antibody, MADD antibody, madd antibody, Madd antibody
    Background

    Synonyms: Differentially expressed in normal and neoplastic cells, FLJ35600, IG20, Insulinoma glucagonoma clone 20, KIAA0358, MADD, MADD_HUMAN, MAP kinase-activating death domain protein, Rab3 GDP/GTP exchange factor, RAB3GEP, DENN

    Background: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

    Gene ID
    8567
    UniProt
    Q8WXG6
    Pathways
    Caspase Cascade in Apoptosis
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