KCTD17 antibody (AA 1-100)

Catalog No. ABIN6943866

Product Details anti-KCTD17 Antibody

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Binding Specificity: AA 1-100

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD17 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD17

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KCTD17

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Alternative Name: KCTD17 (KCTD17 Products)

Synonyms: N28155 antibody, AA414907 antibody, AW742389 antibody, 2900008M13Rik antibody, RGD1311154 antibody, potassium channel tetramerization domain containing 17 antibody, potassium channel tetramerisation domain containing 17 antibody, KCTD17 antibody, Kctd17 antibody

Background:

Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.

Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

Gene ID: 79734

UniProt: Q8N5Z5