Gephyrin antibody
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- Target See all Gephyrin (GPHN) Antibodies
- Gephyrin (GPHN)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Gephyrin antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein within human Gephyrin aa 1-100.
- Clone
- 7A1
- Isotype
- IgG
- Top Product
- Discover our top product GPHN Primary Antibody
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- Application Notes
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Gephyrin (GPHN)
- Alternative Name
- Gephyrin (GPHN Products)
- Background
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Synonyms: Gephyrin, Molybdopterin adenylyltransferase, Domain G, Molybdopterin molybdenumtransferase, Domain E, MPT adenylyltransferase, MPT Mo-transferase, GPHN, GPH, KIAA1385
Background: The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.
- Gene ID
- 10243
- UniProt
- Q9NQX3
- Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
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