FYB1 antibody
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- Target See all FYB1 products
- FYB1 (FYN-Binding Protein 1 (FYB1))
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This FYB1 antibody is un-conjugated
- Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein within C-terminal human FYB.
- Clone
- 1F10
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- FYB1 (FYN-Binding Protein 1 (FYB1))
- Alternative Name
- FYB1 (FYB1 Products)
- Synonyms
- ADAP antibody, PRO0823 antibody, SLAP-130 antibody, FYN binding protein 1 antibody, FYB1 antibody
- Background
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Synonyms: FYN-binding protein 1, Adhesion and degranulation promoting adaptor protein, ADAP, FYB-120/130, p120/p130, FYN-T-binding protein, SLAP-130, SLP-76-associated phosphoprotein, SLAP130, FYB
Background: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
- Gene ID
- 2533
- UniProt
- O15117
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