FPA antibody (AA 20-120) (AbBy Fluor® 488)

Catalog No. ABIN6943456

Product Details anti-FPA Antibody (AbBy Fluor® 488)

Target: FPA (Fibrinopeptide A (FPA))

Binding Specificity: AA 20-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPA antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fibrinopeptide A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FPA

Target: FPA (Fibrinopeptide A (FPA))

Alternative Name: Fibrinopeptide A (FPA Products)

Synonyms: Fib2 antibody, fibrinogen alpha chain antibody, FGA antibody

Background:

Synonyms: FGA, Fib2, FIBA_HUMAN, Fibrinogen alpha chain, fibrinogen alpha chain isoform alpha preproprotein, Fibrinogen alpha/alpha E chain [Precursor], fibrinogen alpha chain isoform alpha-E preproprotein, fibrinogen alpha chain isoform alpha preproprotein.

Background: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]

Gene ID: 2243

UniProt: P02671