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EXOSC5 antibody (AA 141-235) (AbBy Fluor® 647)

EXOSC5 Reactivity: Mouse IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN6943380
  • Target See all EXOSC5 Antibodies
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Binding Specificity
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 141-235
    Reactivity
    • 17
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 26
    • 5
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC5 antibody is conjugated to AbBy Fluor® 647
    Application
    • 12
    • 12
    • 12
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EXOSC5
    Isotype
    IgG
    Top Product
    Discover our top product EXOSC5 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Alternative Name
    EXOSC5 (EXOSC5 Products)
    Synonyms
    si:ch211-194n6.2 antibody, zgc:153707 antibody, EXOSC5 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody, hRrp46p antibody, p12B antibody, D7Wsu180e antibody, exosome component 5 antibody, exosc5 antibody, EXOSC5 antibody, Exosc5 antibody
    Background

    Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.

    Gene ID
    56915
    UniProt
    Q9NQT4
    Pathways
    SARS-CoV-2 Protein Interactome
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