EXOC3L2 antibody (AA 151-250) (Cy3)

Catalog No. ABIN6943353

Product Details anti-EXOC3L2 Antibody (Cy3)

Target: EXOC3L2 (Exocyst Complex Component 3-Like 2 (EXOC3L2))

Binding Specificity: AA 151-250

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC3L2 antibody is conjugated to Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOC3L2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EXOC3L2

Target: EXOC3L2 (Exocyst Complex Component 3-Like 2 (EXOC3L2))

Alternative Name: EXOC3L2 (EXOC3L2 Products)

Synonyms: XTP7 antibody, exocyst complex component 3 like 2 antibody, EXOC3L2 antibody

Background:

Synonyms: Exocyst complex component 3 like, Exocyst complex component 3 like protein 2, FLJ36147, EX3L2_HUMAN, HBV X transactivated gene 7 protein, HBV XAg transactivated protein 7, MGC16332, OTTHUMP00000207128, OTTMUSP00000045827, Protein 7 transactivated by hepatitis B virus X antigen (HBxAg), XTP7.

Background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex.

Gene ID: 90332

UniProt: Q2M3D2