EXOC1 antibody (AA 701-800) (Biotin)

Catalog No. ABIN6943330

Product Details anti-EXOC1 Antibody (Biotin)

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Binding Specificity: AA 701-800

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOC1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for EXOC1

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Alternative Name: EXOC1 (EXOC1 Products)

Synonyms: CG3885 antibody, Dmel\\CG3885 antibody, Sec3 antibody, sec3l1 antibody, zgc:64145 antibody, wu:fb58e03 antibody, SEC3L1 antibody, MGC165876 antibody, DKFZp459K086 antibody, BM-102 antibody, SEC3 antibody, SEC3P antibody, 2810407P21Rik antibody, A730011E05Rik antibody, Sec3l1 antibody, Sec3p antibody, Secretory 3 antibody, exocyst complex component 1 antibody, Exocyst complex component 1 antibody, Sec3 antibody, LOC475149 antibody, exoc1 antibody, EXOC1 antibody, LOC582238 antibody, LOC100566235 antibody, Exoc1 antibody, sec-3 antibody

Background:

Synonyms: BM-012, exoc1, EXOC1_HUMAN, Exocyst complex component 1, Exocyst complex component Sec3, FLJ10893, SEC3, SEC3 like 1, SEC3L1, SEC3P.

Background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Exo70, also known as EXOC7 (exocyst complex component 7), EXOC1 or 2-5-3p, is a 735 amino acid peripheral membrane protein that is a component of the exocyst complex. Localized to the cytoplasm and the cell membrane, Exo70 plays an essential role in the docking of exocystic vesicles to target sites on the plasma membrane and, specifically, may be involved in insulin-induced protein docking within the cell. Four isoforms of Exo70 are expressed due to alternative splicing events.

Gene ID: 55763

UniProt: Q9NV70

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis