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Envoplakin-Like antibody (AA 101-200) (AbBy Fluor® 488)

EVPLL Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN6943317
  • Target See all Envoplakin-Like (EVPLL) products
    Envoplakin-Like (EVPLL)
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 101-200
    Reactivity
    Human
    Host
    • 29
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Envoplakin-Like antibody is conjugated to AbBy Fluor® 488
    Application
    • 15
    • 15
    • 12
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EVPLL
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Envoplakin-Like (EVPLL)
    Alternative Name
    EVPLL (EVPLL Products)
    Synonyms
    envoplakin like antibody, EVPLL antibody
    Background

    Synonyms: Envoplakin like, Envoplakin-like protein, EVPLL, EVPLL_HUMAN,

    Background: EVPLL (envoplakin-like protein) is a 301 amino acid protein that belongs to the plakin or cytolinker family. The gene encoding EVPLL maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Gene ID
    645027
    UniProt
    A8MZ36
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