DDX6 antibody
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- Target See all DDX6 Antibodies
- DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This DDX6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein within human DDX6 aa 100-300
- Clone
- 15C2
- Isotype
- IgG
- Top Product
- Discover our top product DDX6 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))
- Alternative Name
- DDX6 (DDX6 Products)
- Synonyms
- si:ch211-147p17.1 antibody, P54H antibody, Xp54 antibody, hlr2 antibody, me31b antibody, p54 antibody, rck antibody, HLR2 antibody, P54 antibody, RCK antibody, p54h antibody, RGD1564560 antibody, 1110001P04Rik antibody, E230023J21Rik antibody, mRCK/P54 antibody, DEAD-box helicase 6 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 6 antibody, DEAD-box helicase 6 L homeolog antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 antibody, DDX6 antibody, ddx6 antibody, ddx6.L antibody, Ddx6 antibody
- Background
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Synonyms: Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK.
Background: RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.
- Gene ID
- 1656
- UniProt
- P26196
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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