Claudin 5 antibody

Catalog No. ABIN6942582

Product Details anti-Claudin 5 Antibody

Target: Claudin 5 (CLDN5)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Claudin 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Human Claudin 5 aa 100 to the C-terminus

Clone: 8C5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Claudin 5

Target: Claudin 5 (CLDN5)

Alternative Name: Claudin 5 (CLDN5 Products)

Background:

Synonyms: Claudin-5, Transmembrane protein deleted in VCFS, TMDVCF, CLDN5

Background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact, made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water, etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Gene ID: 7122

UniProt: O00501

Pathways: Hepatitis C