Calcitonin antibody (AA 85-116) (AbBy Fluor® 350)

Catalog No. ABIN6942316

Product Details anti-Calcitonin Antibody (AbBy Fluor® 350)

Target: Calcitonin (Calca)

Binding Specificity: AA 85-116

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calcitonin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Calcitonin

Target: Calcitonin (Calca)

Alternative Name: Calcitonin (Calca Products)

Synonyms: calcitonin-related polypeptide alpha antibody, CALCA antibody

Background:

Synonyms: Alpha CGRP, CALC 1, CALC A, CALC1, CALCA, Calcitonin related polypeptide alpha, CGRP 1, CGRP, CGRP I, CGRP-1, CGRPI, CGRP1, CT, Katacalcin, KC, MGC126648, alpha type CGRP, calcitonin 1, calcitonin gene related peptide 1, calcitonin gene related peptide I, calcitonin isoform CT preproprotein.

Background: Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Gene ID: 796

UniProt: P01258