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ABCC2 antibody

ABCC2 Reactivity: Human WB, IHC (p), IF (cc), IF (p), FACS Host: Rabbit Monoclonal 2G9 unconjugated
Catalog No. ABIN6942024
  • Target See all ABCC2 Antibodies
    ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
    Reactivity
    • 37
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 6
    Rabbit
    Clonality
    • 27
    • 12
    Monoclonal
    Conjugate
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ABCC2 antibody is un-conjugated
    Application
    • 18
    • 13
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    Human ABCC2 aa 800-1000
    Clone
    2G9
    Isotype
    IgG
    Top Product
    Discover our top product ABCC2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
    Alternative Name
    ABCC2 (ABCC2 Products)
    Synonyms
    ABC30 antibody, CMOAT antibody, DJS antibody, MRP2 antibody, cMRP antibody, AI173996 antibody, Abc30 antibody, Cmoat antibody, Mrp2 antibody, ATP binding cassette subfamily C member 2 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antibody, ABCC2 antibody, Abcc2 antibody
    Background

    Synonyms: Canalicular multispecific organic anion transporter 1, ATP-binding cassette sub-family C member 2, Canalicular multidrug resistance protein, Multidrug resistance-associated protein 2, ABCC2, CMOAT, CMOAT1, CMRP, MRP2

    Background: Multi-drug resistance protein 2 (MRP2), also known as ABCC2, is an ATP binding cassette (ABC) transporter responsible for biliary excretion of xenobiotics, endobiotics, and their metabolites. Deficiency in ABCC2 results in the clinical disorder Dubin-Johnson syndrome. MRP2 is found to be expressed in a variety of human cancers, and is associated with resistance of tumor cells to various anticancer drugs including cisplatin. The predicted molecular weight of MRP2 is 174 kDa, while mature MRP2 usually has a slower migration around 190-250 kDa due to the glycosylation. Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.

    Gene ID
    1244
    UniProt
    Q92887
    Pathways
    Hormone Transport
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