4E-BP1/2/3 antibody (pThr45)
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- Target See all 4E-BP1/2/3 products
- 4E-BP1/2/3
- Binding Specificity
- pThr45
- Reactivity
- Human, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This 4E-BP1/2/3 antibody is un-conjugated
- Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Synthetic peptide derived from human 4E-BP1/2/3 (Thr 45), around 35-55aa.
- Clone
- 3G2
- Isotype
- IgG2a
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- 4E-BP1/2/3
- Abstract
- 4E-BP1/2/3 Products
- Background
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Synonyms: ABCA1 phospho S2054, p-ABCA1 phospho S2054, ATP binding cassette transporter A1, ABC 1, ABC Transporter 1, ABC1, ABCA 1, ABCA1, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding Cassette Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD, ABCA1_HUMAN.
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
- Gene ID
- 19
- UniProt
- O95477
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