Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD3 epsilon antibody

CD3E Reactivity: Human, Monkey FACS, IF, Act, ProA Host: Mouse Monoclonal CRIS-7 unconjugated
Catalog No. ABIN6941029
  • Target See all CD3 epsilon (CD3E) Antibodies
    CD3 epsilon (CD3E)
    Reactivity
    • 229
    • 158
    • 51
    • 42
    • 17
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human, Monkey
    Host
    • 139
    • 122
    • 34
    • 23
    • 20
    • 8
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 230
    • 112
    • 7
    Monoclonal
    Conjugate
    • 138
    • 32
    • 27
    • 20
    • 17
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD3 epsilon antibody is un-conjugated
    Application
    • 252
    • 145
    • 105
    • 82
    • 78
    • 69
    • 27
    • 27
    • 25
    • 21
    • 14
    • 13
    • 12
    • 12
    • 8
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Activation (Act), Proliferation Assay (ProA)
    Specificity
    Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
    Immunogen
    Stimulated human leukocytes
    Clone
    CRIS-7
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD3E Primary Antibody
  • Application Notes

    Positive Control: Jurkat cells. Tonsil and lymph node.

    Known Application: Induce T cell activation and proliferation (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    CD3 epsilon (CD3E)
    Alternative Name
    CD3E (CD3E Products)
    Molecular Weight
    20kDa
    Gene ID
    916
    UniProt
    P07766
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
You are here:
Support