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RCAS1 antibody

EBAG9 Reactivity: Human IHC, IF, StM Host: Mouse Monoclonal CPTC-EBAG9-1 unconjugated
Catalog No. ABIN6941019
  • Target See all RCAS1 (EBAG9) Antibodies
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    Reactivity
    • 38
    • 32
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 8
    • 2
    Mouse
    Clonality
    • 44
    • 9
    Monoclonal
    Conjugate
    • 27
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCAS1 antibody is un-conjugated
    Application
    • 24
    • 16
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length EBAG9 protein
    Clone
    CPTC-EBAG9-1
    Isotype
    IgG2c kappa
    Top Product
    Discover our top product EBAG9 Primary Antibody
  • Application Notes

    Positive Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.

    Known Application: Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    Alternative Name
    EBAG9 (EBAG9 Products)
    Synonyms
    EB9 antibody, PDAF antibody, MGC56608 antibody, zgc:56608 antibody, MGC84425 antibody, EBAG9 antibody, AI835379 antibody, Rcas1 antibody, RCAS1 antibody, eb9 antibody, pdaf antibody, rcas1 antibody, estrogen receptor binding site associated, antigen, 9 antibody, estrogen receptor binding site associated, antigen, 9 L homeolog antibody, estrogen receptor-binding fragment-associated gene 9 antibody, EBAG9 antibody, ebag9 antibody, ebag9.L antibody, Ebag9 antibody
    Background
    EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
    Molecular Weight
    32kDa
    Gene ID
    9166
    UniProt
    O00559
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