Recombinant VLDLR antibody (C-Term)

Catalog No. ABIN6940887

Product Details anti-VLDLR Antibody

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Antibody Type: Recombinant Antibody

Binding Specificity: C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VLDLR antibody is un-conjugated

Application: ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogen: Recombinant human VLDLR fragment from c-terminal

Clone: VLDLR-2896R

Isotype: IgG

Application Details

Application Notes:

Positive Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

Known Application: ELISA (For coating, order antibody without BSA) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Alternative Name: VLDLR (VLDLR Products)

Synonyms: CARMQ1 antibody, CHRMQ1 antibody, VLDLRCH antibody, AA408956 antibody, AI451093 antibody, AW047288 antibody, vldlr antibody, very low density lipoprotein receptor antibody, very low density lipoprotein receptor S homeolog antibody, VLDLR antibody, Vldlr antibody, vldlr.S antibody

Background: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Molecular Weight: 143-161kDa

Gene ID: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin