Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Ubiquitin B antibody (AA 1-119)

UBB Reactivity: Human WB, IHC, ELISA, StM, Coat Host: Mouse Monoclonal UBB-2122 unconjugated
Catalog No. ABIN6940845
  • Target See all Ubiquitin B (UBB) Antibodies
    Ubiquitin B (UBB)
    Binding Specificity
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-119
    Reactivity
    • 41
    • 24
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 5
    Mouse
    Clonality
    • 32
    • 9
    Monoclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Ubiquitin B antibody is un-conjugated
    Application
    • 20
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
    Clone
    UBB-2122
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product UBB Primary Antibody
  • Application Notes

    Positive Control: HeLa or Jurkat cells. Alzheimer's Brain.

    Known Application: ELISA (For coating, order Ab without BSA), Western Blot (0.5-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    Ubiquitin B (UBB)
    Alternative Name
    UBB (UBB Products)
    Synonyms
    AL033289 antibody, Rps27a antibody, Uba52 antibody, Ubb2 antibody, Ubc antibody, UBC antibody, Ubiquitin antibody, UBB antibody, Ubi-p63E antibody, im:6892314 antibody, si:ch211-202a12.3 antibody, ubc antibody, zUBC antibody, zgc:172187 antibody, ubiquitin B antibody, ubiquitin C antibody, UBB antibody, Ubb antibody, UBC antibody, ubb antibody
    Background
    Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.
    Molecular Weight
    9kDa
    Gene ID
    7314
    UniProt
    P62979, P62987, P62988
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway
You are here:
Support