Tyrosinase-Related Protein 1 antibody
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- Target See all Tyrosinase-Related Protein 1 (TYRP1) Antibodies
- Tyrosinase-Related Protein 1 (TYRP1)
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Tyrosinase-Related Protein 1 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Purification
- Purified by Protein A/G
- Immunogen
- SK-MEL-23 cells
- Clone
- TA99
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TYRP1 Primary Antibody
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anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 Reactivity: Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Sheep, Cow, Guinea Pig, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 Reactivity: Human IHC, ELISA, StM, Coat Host: Rabbit Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 Reactivity: Human IHC, ELISA, StM, Coat Host: Mouse Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 Reactivity: Human, Mouse IHC, StM Host: Rabbit Monoclonal TYRP1-1564R unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 Reactivity: Human, Mouse IHC, StM Host: Rabbit Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 Reactivity: Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio), Monkey, Chicken, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Melanoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen only) (0.5-1 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- Tyrosinase-Related Protein 1 (TYRP1)
- Alternative Name
- TYRP1 (TYRP1 Products)
- Molecular Weight
- 75kDa
- Gene ID
- 7306
- UniProt
- P17643
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