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Transferrin Receptor antibody

TFRC Reactivity: Human FACS, WB, IF Host: Mouse Monoclonal DF1513 unconjugated
Catalog No. ABIN6940694
  • Target See all Transferrin Receptor (TFRC) Antibodies
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Reactivity
    • 192
    • 85
    • 28
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 110
    • 107
    • 30
    • 1
    • 1
    Mouse
    Clonality
    • 152
    • 95
    • 1
    Monoclonal
    Conjugate
    • 114
    • 25
    • 21
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Transferrin Receptor antibody is un-conjugated
    Application
    • 142
    • 131
    • 67
    • 66
    • 53
    • 38
    • 25
    • 21
    • 19
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
    Purification
    Purified by Protein A/G
    Immunogen
    KG1 acute myeloid leukemia cell line
    Clone
    DF1513
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TFRC Primary Antibody
  • Application Notes

    Positive Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Alternative Name
    TFRC (TFRC Products)
    Molecular Weight
    85-95kDa (monomer), 190kDa (dimer)
    Gene ID
    7037
    UniProt
    P02786
    Pathways
    Transition Metal Ion Homeostasis
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