SULT1E1 antibody

Catalog No. ABIN6940673

Product Details anti-SULT1E1 Antibody

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SULT1E1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human SULT1E1 protein

Clone: CPTC-SULT1E1-1

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: HEP G2, liver, intestine and kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Alternative Name: SULT1E1 (SULT1E1 Products)

Synonyms: STE antibody, St1 antibody, EST antibody, ST1E1 antibody, Ste antibody, EST-1 antibody, est-1 antibody, ste antibody, sult1e1 antibody, sult1e1.S antibody, sulfotransferase family 1E member 1 antibody, sulfotransferase family 1E, estrogen-preferring, member 1 antibody, estrogen sulfotransferase antibody, sulfotransferase family 1E, member 1 antibody, sulfotransferase family 1E member 1 L homeolog antibody, Sult1e1 antibody, SULT1E1 antibody, St1 antibody, CpipJ_CPIJ012993 antibody, CpipJ_CPIJ014515 antibody, LOC482182 antibody, sult1e1.L antibody

Background: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

Molecular Weight: 35kDa

Gene ID: 6783

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis