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SREBF2 antibody

SREBF2 Reactivity: Human ELISA, Coat Host: Mouse Monoclonal SREBP2-1579 unconjugated
Catalog No. ABIN6940660
  • Target See all SREBF2 Antibodies
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Reactivity
    • 65
    • 32
    • 31
    • 16
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 6
    • 1
    Mouse
    Clonality
    • 61
    • 5
    Monoclonal
    Conjugate
    • 31
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SREBF2 antibody is un-conjugated
    Application
    • 52
    • 27
    • 21
    • 18
    • 11
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human SREBF2 protein
    Clone
    SREBP2-1579
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product SREBF2 Primary Antibody
  • Application Notes

    Positive Control: Ubiqutious expression in adult and fetal tissues. Hep2 or HeLa cells.

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Alternative Name
    SREBF2 (SREBF2 Products)
    Synonyms
    SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody
    Background
    The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
    Molecular Weight
    68/125kDa
    Gene ID
    6721
    UniProt
    Q12772
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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