Recombinant GLUT1 antibody (AA 203-305)
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- Target See all GLUT1 (SLC2A1) Antibodies
- GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- AA 203-305
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GLUT1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
- Specificity
- Recognizes a protein of 55 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary)
- Clone
- RGLUT1-2476
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product SLC2A1 Primary Antibody
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- Application Notes
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Positive Control: K562, A431, MDA-MB-231 cells or erythrocytes. Mesothelioma or breast, colon and ovarian carcinoma.
Known Application: ELISA (For coating use Ab at 1-2 μg/mL order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
- Alternative Name
- SLC2A1 (SLC2A1 Products)
- Synonyms
- DYT17 antibody, DYT18 antibody, DYT9 antibody, EIG12 antibody, GLUT antibody, GLUT1 antibody, GLUT1DS antibody, HTLVR antibody, PED antibody, Glut-1 antibody, Glut1 antibody, GLUTB antibody, GTG1 antibody, Gtg3 antibody, RATGTG1 antibody, SLC2A1 antibody, GLT1 antibody, GLUCOSE TRANSPORTER 1 antibody, T21H19.70 antibody, T21H19_70 antibody, plastidic GLC translocator antibody, glut1 antibody, ped antibody, slc2a1 antibody, slc2a14 antibody, solute carrier family 2 member 1 antibody, solute carrier family 2 (facilitated glucose transporter), member 1 antibody, plastidic GLC translocator antibody, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog antibody, SLC2A1 antibody, Slc2a1 antibody, PGLCT antibody, slc2a1.L antibody
- Molecular Weight
- 55kDa
- Gene ID
- 6513
- UniProt
- P11166
- Pathways
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effect
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