SHBG antibody

Catalog No. ABIN6940577

Product Details anti-SHBG Antibody

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHBG antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)

Specificity: Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human SHBG protein

Clone: SPM605

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Liver, Placenta or Testis.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Alternative Name: SHBG (SHBG Products)

Synonyms: ABP antibody, SBP antibody, TEBG antibody, Abpa antibody, shbgl antibody, wu:fb66h07 antibody, wu:fd55b08 antibody, zgc:123063 antibody, shbg antibody, sex hormone binding globulin antibody, sex hormone-binding globulin antibody, sex hormone binding globulin L homeolog antibody, SHBG antibody, Shbg antibody, shbg antibody, shbg.L antibody

Molecular Weight: 45kDa

Gene ID: 6462

UniProt: P04278

Pathways: Hormone Transport