ENAH antibody (AA 485-589)

Catalog No. ABIN6940390

Product Details anti-ENAH Antibody

Target: ENAH (Enabled Homolog (ENAH))

Binding Specificity: AA 485-589

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ENAH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogen: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Clone: ENAH-1988

Isotype: IgG2c kappa

Application Details

Application Notes:

Positive Control: MCF-7 cells. Uterus.

Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ENAH

Target: ENAH (Enabled Homolog (ENAH))

Alternative Name: ENAH (ENAH Products)

Synonyms: ENA antibody, MENA antibody, NDPP1 antibody, AI464316 antibody, AW045240 antibody, Mena antibody, Ndpp1 antibody, WBP8 antibody, id:ibd2798 antibody, si:ch211-215p14.1 antibody, zgc:103638 antibody, ENAH, actin regulator antibody, enabled homolog (Drosophila) antibody, Enah antibody, ENAH antibody, enah antibody

Background: The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Molecular Weight: 80/88/140kDa

Gene ID: 55740

UniProt: Q8N8S7