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PD-1 antibody

PDCD1 Reactivity: Human FACS, IHC, IF, StM, ISt Host: Mouse Monoclonal PDCD1-922 unconjugated
Catalog No. ABIN6940269
  • Target See all PD-1 (PDCD1) Antibodies
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Reactivity
    • 144
    • 77
    • 25
    • 5
    • 3
    • 1
    Human
    Host
    • 82
    • 64
    • 25
    • 13
    • 11
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 135
    • 62
    • 2
    Monoclonal
    Conjugate
    • 94
    • 15
    • 13
    • 11
    • 7
    • 5
    • 4
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PD-1 antibody is un-conjugated
    Application
    • 129
    • 58
    • 44
    • 37
    • 34
    • 19
    • 13
    • 13
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    • 10
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM), Immunostaining (ISt)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human PDCD1 protein
    Clone
    PDCD1-922
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • Application Notes

    Positive Control: TY cells. Tonsil.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Alternative Name
    PDCD1 (PDCD1 Products)
    Synonyms
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    Background
    PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
    Molecular Weight
    55kDa
    Gene ID
    5133
    UniProt
    Q15116
    Pathways
    Cancer Immune Checkpoints
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