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LHCGR antibody (AA 70-410)

LHCGR Reactivity: Human IF, FACS Host: Mouse Monoclonal LHCGR-1415 unconjugated
Catalog No. ABIN6939962
  • Target See all LHCGR Antibodies
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    Binding Specificity
    • 23
    • 15
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-410
    Reactivity
    • 78
    • 31
    • 29
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 26
    • 1
    Mouse
    Clonality
    • 57
    • 26
    Monoclonal
    Conjugate
    • 31
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LHCGR antibody is un-conjugated
    Application
    • 50
    • 31
    • 27
    • 20
    • 14
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
    Clone
    LHCGR-1415
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product LHCGR Primary Antibody
  • Application Notes

    Positive Control: HepG2 or Jurkat cells. Ovary or Testis.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    Alternative Name
    LHCGR (LHCGR Products)
    Synonyms
    HHG antibody, LCGR antibody, LGR2 antibody, LH/CG-R antibody, LH/CGR antibody, LHR antibody, LHRHR antibody, LSH-R antibody, ULG5 antibody, Gpcr19-rs1 antibody, LH-R antibody, Lhr antibody, LSHR antibody, lhr antibody, GTHR-II antibody, zfGTHR-II antibody, LHCGR antibody, LOC100222883 antibody, lh-r antibody, LOC100305044 antibody, luteinizing hormone/choriogonadotropin receptor antibody, luteinizing hormone/choriogonadotropin receptor L homeolog antibody, luteinizing hormone receptor antibody, LHCGR antibody, Lhcgr antibody, lhcgr antibody, lhcgr.L antibody, lhr antibody, LOC100305044 antibody
    Molecular Weight
    78-85kDa
    Gene ID
    3973
    UniProt
    P22888
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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