KRT16 antibody (C-Term)

Catalog No. ABIN6939917

Product Details anti-KRT16 Antibody

Target: KRT16 (Keratin 16 (KRT16))

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: A synthetic peptide from the C-terminal of human Cytokeratin 16

Clone: LL025

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for KRT16

Target: KRT16 (Keratin 16 (KRT16))

Alternative Name: KRT16 (KRT16 Products)

Synonyms: CK16 antibody, FNEPPK antibody, K16 antibody, K1CP antibody, KRT16A antibody, NEPPK antibody, AI324768 antibody, Krt1-16 antibody, Ka16 antibody, KRT16 antibody, Krt16 antibody, keratin 16 antibody, keratin 16, type I S homeolog antibody, keratin, type I cytoskeletal 16 antibody, KRT16 antibody, Krt16 antibody, krt16.S antibody, LOC101108147 antibody, LOC100714013 antibody

Background: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

Molecular Weight: 48kDa

Gene ID: 3868

UniProt: P08779