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GP2 antibody (AA 35-179)

GP2 Reactivity: Human IHC, ELISA, Coat, StM Host: Mouse Monoclonal GP2-1805 unconjugated
Catalog No. ABIN6939544
  • Target See all GP2 products
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Binding Specificity
    • 27
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    Reactivity
    • 47
    • 8
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 32
    • 24
    Mouse
    Clonality
    • 28
    • 28
    Monoclonal
    Conjugate
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GP2 antibody is un-conjugated
    Application
    • 33
    • 31
    • 23
    • 19
    • 19
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
    Clone
    GP2-1805
    Isotype
    IgG2c kappa
  • Application Notes

    Positive Control: PANC-1 cells. Pancreas.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Alternative Name
    GP2 (GP2 Products)
    Synonyms
    ZAP75 antibody, 2310037I18Rik antibody, AV060639 antibody, gp80 antibody, glycoprotein 2 antibody, glycoprotein 2 (zymogen granule membrane) antibody, GP2 antibody, Gp2 antibody
    Target Type
    Viral Protein
    Background
    GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
    Molecular Weight
    59kDa
    Gene ID
    2813
    UniProt
    P55259
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