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FUT3 antibody

FUT3 Reactivity: Human, Guinea Pig IHC, IF, ISt, StM Host: Mouse Monoclonal 2-25LE-same as LWB01 unconjugated
Catalog No. ABIN6939469
  • Target See all FUT3 Antibodies
    FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))
    Reactivity
    • 47
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Guinea Pig
    Host
    • 40
    • 7
    Mouse
    Clonality
    • 42
    • 5
    Monoclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FUT3 antibody is un-conjugated
    Application
    • 34
    • 22
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Mucin isolated from a human ovarian cyst fluid
    Clone
    2-25LE-same as LWB01
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FUT3 Primary Antibody
  • Application Notes

    Positive Control: Colon.

    Known Application: Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))
    Alternative Name
    FUT3 (FUT3 Products)
    Synonyms
    CD174 antibody, FT3B antibody, FucT-III antibody, LE antibody, Les antibody, fut356 antibody, FUT3 antibody, ATFUT3 antibody, F1M20.10 antibody, F1M20_10 antibody, fucosyltransferase 3 antibody, fucosyltransferase 3 (Lewis blood group) antibody, fucosyltransferase 3 (Lewis blood group) L homeolog antibody, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) antibody, fucosyltransferase 3 antibody, galactoside 3(4)-L-fucosyltransferase antibody, FUT3 antibody, fut3.L antibody, fut3 antibody, LOC697452 antibody, LOC697582 antibody
    Background
    The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.
    Molecular Weight
    45kDa
    Gene ID
    2525
    UniProt
    P21217
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