FSHB antibody

Catalog No. ABIN6939444

Product Details anti-FSHB Antibody

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FSHB antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificity: This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length hFSH beta sub-unit

Clone: FSHb-1062

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Anterior Pituitary.

Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FSHB

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Alternative Name: FSHB (FSHB Products)

Synonyms: gthI antibody, fsh-beta antibody, LOC100136594 antibody, FSHB antibody, LOC100218526 antibody, FSH antibody, Fshbeta antibody, FSH-beta antibody, follicle stimulating hormone, beta polypeptide antibody, follicle stimulating hormone beta subunit L homeolog antibody, follcle-stimulating hormone beta subunit antibody, follicle stimulating hormone beta subunit antibody, follicle stimulating hormone beta antibody, follitropin subunit beta antibody, fshb antibody, fshb.L antibody, LOC100136594 antibody, FSHB antibody, Fshb antibody

Molecular Weight: 22kDa

Gene ID: 2488

UniProt: P01225

Pathways: Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process