Recombinant Frataxin antibody (AA 57-210)
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- Target See all Frataxin (FXN) Antibodies
- Frataxin (FXN)
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- AA 57-210
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Frataxin antibody is un-conjugated
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Application
- ELISA, Coating (Coat)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
- Clone
- RFXN-2124
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product FXN Primary Antibody
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- Application Notes
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Positive Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- Frataxin (FXN)
- Alternative Name
- FXN (FXN Products)
- Synonyms
- zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
- Background
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
- Molecular Weight
- 14kDa
- Gene ID
- 2395
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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