Fibronectin 1 antibody (AA 467-595)

Catalog No. ABIN6939415

Product Details anti-Fibronectin 1 Antibody

Target: Fibronectin 1 (FN1)

Binding Specificity: AA 467-595

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Specificity: Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.

Purification: Purified by Protein A/G

Immunogen: Recombinant fragment (around aa 467-595) of human fibronectin protein (exact sequence is proprietary)

Clone: FN1-2949

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: SW156 cells or Kidney.

Known Application: ELISA (For coating, order Ab without BSA),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: FN1 (FN1 Products)

Synonyms: FN1 antibody, FN antibody, cig antibody, fibronectin antibody, finc antibody, lets antibody, msf antibody, Fn antibody, fn2 antibody, fb80d10 antibody, wu:fb80d10 antibody, CIG antibody, ED-B antibody, FINC antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody, E330027I09 antibody, Fn-1 antibody, FIBNEC antibody, fn-1 antibody, fibronectin 1 antibody, fibronectin 1a antibody, fibronectin 1 S homeolog antibody, FN1 antibody, fn1 antibody, fn1a antibody, Fn1 antibody, fn1.S antibody

Molecular Weight: 220kDa (monomer), 440kDa (dimer)

Gene ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy