FABP5 antibody

Catalog No. ABIN6939368

Product Details anti-FABP5 Antibody

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: Recombinant human full-length FABP5 protein

Clone: CPTC-FABP5-3

Isotype: IgG2a kappa

Application Details

Application Notes:

Positive Control: MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

Known Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10mM PBS with 0.05% BSA & 0.05% azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FABP5

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Alternative Name: FABP5 (FABP5 Products)

Synonyms: E-FABP antibody, EFABP antibody, KFABP antibody, PA-FABP antibody, PAFABP antibody, FABP5 antibody, Fabpe antibody, Klbp antibody, mal1 antibody, C-FABP antibody, DA11 antibody, FABP5L1 antibody, fatty acid binding protein 5 antibody, fatty acid binding protein 5, epidermal antibody, fatty acid binding protein 5 (psoriasis-associated) antibody, fatty acid binding protein 5 pseudogene 1 antibody, cationic amino acid transporter 3 pseudogene antibody, FABP5 antibody, Fabp5 antibody, FABP5P1 antibody, LOC609554 antibody

Background: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

Molecular Weight: 15.4kDa

Gene ID: 2171

UniProt: Q01469