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DNMT1 antibody (AA 767-912)

DNMT1 Reactivity: Human IHC, ISt, StM Host: Mouse Monoclonal DNMT1-2061 unconjugated
Catalog No. ABIN6939246
  • Target See all DNMT1 Antibodies
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    Binding Specificity
    • 22
    • 21
    • 16
    • 12
    • 12
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 767-912
    Reactivity
    • 188
    • 54
    • 45
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 152
    • 36
    • 1
    • 1
    Mouse
    Clonality
    • 142
    • 48
    Monoclonal
    Conjugate
    • 74
    • 15
    • 13
    • 11
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This DNMT1 antibody is un-conjugated
    Application
    • 114
    • 63
    • 43
    • 38
    • 30
    • 28
    • 19
    • 15
    • 14
    • 13
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
    Clone
    DNMT1-2061
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product DNMT1 Primary Antibody
  • Application Notes

    Positive Control: Raji cells. Tonsil or Placenta.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    Alternative Name
    DNMT1 (DNMT1 Products)
    Synonyms
    cb1075 antibody, cb983 antibody, dmnt1 antibody, fb05h01 antibody, mta antibody, wu:fb05h01 antibody, ADCADN antibody, AIM antibody, CXXC9 antibody, DNMT antibody, HSN1E antibody, MCMT antibody, DDM2 antibody, DECREASED DNA METHYLATION 2 antibody, DMT01 antibody, DMT1 antibody, DNA METHYLTRANSFERASE antibody, DNA METHYLTRANSFERASE 01 antibody, DNA METHYLTRANSFERASE 1 antibody, MET2 antibody, METHYLTRANSFERASE 2 antibody, METHYLTRANSFERASE I antibody, METI antibody, methyltransferase 1 antibody, Cxxc9 antibody, Dnmt antibody, Dnmt1o antibody, MTase antibody, Met-1 antibody, Met1 antibody, MommeD2 antibody, m.MmuI antibody, DNA methyltransferase 1 antibody, DNA (cytosine-5-)-methyltransferase 1 antibody, methyltransferase 1 antibody, DNA methyltransferase (cytosine-5) 1 antibody, DNMT1 antibody, dnmt1 antibody, Dnmt1 antibody, MET1 antibody
    Background
    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
    Molecular Weight
    184kDa
    Gene ID
    1786
    UniProt
    P26358
    Pathways
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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