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CLTA/CLTB antibody (N-Term)

CLTA/CLTB Reactivity: Human IHC, StM Host: Mouse Monoclonal CLC-1421 unconjugated
Catalog No. ABIN6939150
  • Target See all CLTA/CLTB Antibodies
    CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))
    Binding Specificity
    • 3
    • 1
    • 1
    N-Term
    Reactivity
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 3
    • 2
    Monoclonal
    Conjugate
    • 5
    This CLTA/CLTB antibody is un-conjugated
    Application
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
    Purification
    Purified by Protein A/G
    Immunogen
    Purified recombinant N-terminal fragment of human Clathrin Light Chain
    Clone
    CLC-1421
    Isotype
    IgG2b kappa
  • Application Notes

    Positive Control: HeLa cells. Placenta or Prostate Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))
    Alternative Name
    CLTA and CLTB (CLTA/CLTB Products)
    Synonyms
    lca antibody, zgc:73358 antibody, wu:fb61d08 antibody, wu:fj48d06 antibody, LCA antibody, clc antibody, DDBDRAFT_0169251 antibody, DDBDRAFT_0191305 antibody, DDB_0169251 antibody, DDB_0191305 antibody, clcb antibody, clathrin light chain A antibody, clathrin, light chain A antibody, Clathrin light chain antibody, clathrin light chain antibody, clathrin light chain B antibody, Clathrin light chain B antibody, CLTA antibody, clta antibody, clic-1 antibody, CLC1 antibody, clc antibody, CLTB antibody, clcb antibody, CNI00580 antibody, LOC5567495 antibody, CpipJ_CPIJ018056 antibody, PTRG_01988 antibody, PMAA_096950 antibody, SJAG_04517 antibody, TSTA_044110 antibody, PAS_chr1-4_0158 antibody
    Molecular Weight
    31-44kDa
    Gene ID
    1211, 1212
    UniProt
    P09496, P09497
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