Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN6938735

Product Details anti-Uroplakin 3A Antibody

Target: Uroplakin 3A (UPK3A)

Binding Specificity: AA 260-279

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotype: IgG

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HEK293 cells. Bladder carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: UPK3A (UPK3A Products)

Background: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A,Uroplakin 3A (Bladder Carcinoma Marker)
Cellular localisation: Cell surface

Molecular Weight: 30kDa

Gene ID: 7380, 632787

UniProt: O75631