SHBG antibody
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- Target See all SHBG Antibodies
- SHBG (Sex Hormone Binding Globulin (SHBG))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SHBG antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human SHBG protein
- Clone
- SPM605
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product SHBG Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Liver, Placenta or Testis.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- SHBG (Sex Hormone Binding Globulin (SHBG))
- Alternative Name
- SHBG (SHBG Products)
- Synonyms
- ABP antibody, SBP antibody, TEBG antibody, Abpa antibody, shbgl antibody, wu:fb66h07 antibody, wu:fd55b08 antibody, zgc:123063 antibody, shbg antibody, sex hormone binding globulin antibody, sex hormone-binding globulin antibody, sex hormone binding globulin L homeolog antibody, SHBG antibody, Shbg antibody, shbg antibody, shbg.L antibody
- Background
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Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG),Sex Hormone Binding Globulin (SHBG)
Cellular localisation: Cytoplasmic & Extracellular (Secreted) - Molecular Weight
- 45kDa
- Gene ID
- 6462, 632235
- UniProt
- P04278
- Pathways
- Hormone Transport
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