Progesterone antibody

Catalog No. ABIN6938248

Product Details anti-Progesterone Antibody

Target: Progesterone

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Coating (Coat), Radioimmunoassay (RIA)

Specificity: This MAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100 % , 5-beta-Pregnane-3,20-dione: 48 %, 5-alpha-Pregnane-3,20-dione: 26.4 %, 17-alpha-Hydroxyprogesterone: 2.5 % and 20-alpha-Hydroxyprogesterone: 0.04 %. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This MAb may prove useful in identification of ovarian tumors.

Purification: Purified by Protein A/G

Immunogen: Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA)

Clone: 6-5E-10B

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Ovary or Placenta.

Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Not assessed),Radioimmnoassay (RIA)

Restrictions: For Research Use only

Handling

Buffer: 10 mM PBS without BSA and without Azide.

Preservative: Azide free

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for Progesterone

Target: Progesterone

Abstract: Progesterone Products

Target Type: Hormone

Molecular Weight: 314.46Da