LMO2 antibody (AA 23-140)
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- Target See all LMO2 Antibodies
- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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Binding Specificity
- AA 23-140
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LMO2 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)
- Clone
- LMO2-1971
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product LMO2 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
- Alternative Name
- LMO2 (LMO2 Products)
- Synonyms
- Rbtn-2 antibody, Rbtn2 antibody, Rhom-2 antibody, Ttg2 antibody, RBTN2 antibody, RBTNL1 antibody, RHOM2 antibody, TTG2 antibody, wu:fc83a08 antibody, zgc:111930 antibody, LMO-2 antibody, lmo2-A antibody, xlmo2 antibody, rhombotin-2 antibody, LIM domain only 2 antibody, LIM domain only 2 (rhombotin-like 1) antibody, LIM domain only 2 S homeolog antibody, lmo2 antibody, LMO2 antibody, Lmo2 antibody, lmo2.S antibody
- Background
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Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2,LMO2 (B-Cell Marker)
Cellular localisation: Nuclear - Molecular Weight
- 24kDa
- Gene ID
- 4005, 34560
- UniProt
- P25791
- Pathways
- Chromatin Binding
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