HHV8 antibody
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- Target See all HHV8 products
- HHV8 (Herpes Virus Type 8 (HHV8))
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Reactivity
- Herpes Simplex Virus (HSV)
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This HHV8 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunofluorescence (IF), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
- Clone
- LN53
- Isotype
- IgG2c kappa
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- Application Notes
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Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.
Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Buffer
- 10 mM PBS without BSA and without Azide.
- Preservative
- Azide free
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
- Expiry Date
- 24 months
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- Target
- HHV8 (Herpes Virus Type 8 (HHV8))
- Alternative Name
- Human Herpes Virus 8 (HHV8) (HHV8 Products)
- Target Type
- Virus
- Background
- HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
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