GJB1 antibody
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- Target See all GJB1 Antibodies
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GJB1 antibody is un-conjugated
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called 'connexons' that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane therefore, one connexin usually cannot fully substitute for another.
- Cross-Reactivity (Details)
- Human. Mouse. Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human GJB1 protein
- Clone
- GJB1-1753
- Isotype
- IgG
- Top Product
- Discover our top product GJB1 Primary Antibody
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- Application Notes
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Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells. Liver, Kidney, Stomach or Tonsil.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
- Alternative Name
- GJB1 (GJB1 Products)
- Synonyms
- GJIC antibody, cmtx antibody, cmtx1 antibody, connexin-30 antibody, connexin32 antibody, cx30 antibody, cx32 antibody, gja1 antibody, CX32 antibody, GJB1 antibody, AI118175 antibody, Cnx32 antibody, Cx32 antibody, Gjb-1 antibody, CMTX antibody, CMTX1 antibody, gjb1-a antibody, gap junction protein beta 1 antibody, connexin 32 antibody, probable serine/threonine-protein kinase CST antibody, gap junction protein, beta 1 antibody, gap junction protein beta 1 L homeolog antibody, gjb1 antibody, CX32 antibody, LOC9303136 antibody, GJB1 antibody, Gjb1 antibody, gjb1.L antibody
- Background
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Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1,Connexin 32 (Gap Junction Protein)
Cellular localisation: Cytoplasmic and Cell Surface - Molecular Weight
- 27-32kDa
- Gene ID
- 2705, 333303
- UniProt
- P08034
- Pathways
- Cell-Cell Junction Organization
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