ODC1 antibody (CF®488A)

Catalog No. ABIN6936033

Product Details anti-ODC1 Antibody (CF®488A)

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ODC1 antibody is conjugated to CF®488A

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)

Specificity: Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Purification: Purified by Protein A/G

Immunogen: Recombinant human ODC-1 protein

Clone: ODC1-485

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Epithelial cells in normal placenta or prostate carcinoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ODC1 (ODC1 Products)

Molecular Weight: 53kDa

Gene ID: 4953

UniProt: P11926