IgL antibody (CF®488A)

Catalog No. ABIN6934794

Product Details anti-IgL Antibody (CF®488A)

Target: IgL

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IgL antibody is conjugated to CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Specificity: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Purification: Purified by Protein A/G

Immunogen: Purified human IgG myeloma proteins coupled to polyaminostyren microbeads

Clone: HP6054

Isotype: IgG2a kappa

Application Details

Application Notes:

Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IgL

Target: IgL

Abstract: IgL Products

Synonyms: IGL@ antibody, IGLC6 antibody, igl antibody, immunoglobulin lambda locus antibody, IGL antibody, igl@ antibody

Molecular Weight: ~22.5kDa

Gene ID: 3535, 3546

UniProt: P01701, P01842