DCP1A antibody (AA 186-285)

Catalog No. ABIN6923031

Product Details anti-DCP1A Antibody

Target: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Binding Specificity: AA 186-285

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DCP1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant DCP1A.

Sequence: STQLSNLGST ETLEEMPSGS QDKSAPSGHK HLTVEELFGT SLPKEQPAVV GLDSEEMERL PGDASQKEPN SFLPFPFEQL GGAPQSETLG VPSAAHHSVQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DCP1A (NP_060873, 186 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3G4

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DCP1A antibody (ABIN6923031)

Pérez-Vilaró, Fernández-Carrillo, Mensa, Miquel, Sanjuan, Forns, Pérez-Del-Pulgar, Díez: "Hepatitis C virus infection inhibits P-body granule formation in human livers." in: Journal of hepatology, Vol. 62, Issue 4, pp. 785-90, (2015) (PubMed).

Seto, Onizuka, Nakajima-Shimada: "Host cytoplasmic processing bodies assembled by Trypanosoma cruzi during infection exert anti-parasitic activity." in: Parasitology international, Vol. 64, Issue 6, pp. 540-6, (2015) (PubMed).

Amadei, Zander, Yang, Dumelie, Vessey, Lipshitz, Smibert, Kaplan, Miller: "A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 47, pp. 15666-81, (2015) (PubMed).

Haeusler, Donnelly, Periz, Simko, Shaw, Kim, Maragakis, Troncoso, Pandey, Sattler, Rothstein, Wang: "C9orf72 nucleotide repeat structures initiate molecular cascades of disease." in: Nature, Vol. 507, Issue 7491, pp. 195-200, (2014) (PubMed).

Kaehler, Isensee, Hucho, Lehrach, Krobitsch: "5-Fluorouracil affects assembly of stress granules based on RNA incorporation." in: Nucleic acids research, Vol. 42, Issue 10, pp. 6436-47, (2014) (PubMed).

Li, Masaki, Shimakami, Lemon: "hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7199-209, (2014) (PubMed).

Ling, Wong, Li, Chan, Boukamp, Liu: "CCHCR1 interacts with EDC4, suggesting its localization in P-bodies." in: Experimental cell research, Vol. 327, Issue 1, pp. 12-23, (2014) (PubMed).

Seto, Inoue, Nakatani, Yamada, Isomura: "Processing bodies accumulate in human cytomegalovirus-infected cells and do not affect viral replication at high multiplicity of infection." in: Virology, Vol. 458-459, pp. 151-61, (2014) (PubMed).

Perez-Pepe, Slomiansky, Loschi, Luchelli, Neme, Thomas, Boccaccio: "BUHO: a MATLAB script for the study of stress granules and processing bodies by high-throughput image analysis." in: PLoS ONE, Vol. 7, Issue 12, pp. e51495, (2013) (PubMed).

Li, Masaki, Yamane, McGivern, Lemon: "Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1881-6, (2013) (PubMed).

de Vries, Naarmann-de Vries, Urlaub, Lue, Bernhagen, Ostareck, Ostareck-Lederer: "Identification of DEAD-box RNA helicase 6 (DDX6) as a cellular modulator of vascular endothelial growth factor expression under hypoxia." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5815-27, (2013) (PubMed).

Aizer, Kafri, Kalo, Shav-Tal: "The P body protein Dcp1a is hyper-phosphorylated during mitosis." in: PLoS ONE, Vol. 8, Issue 1, pp. e49783, (2013) (PubMed).

Wang, Chen, Wang: "Pdc1 functions in the assembly of P bodies in Schizosaccharomyces pombe." in: Molecular and cellular biology, Vol. 33, Issue 6, pp. 1244-53, (2013) (PubMed).

Cohen-Katsenelson, Wasserman, Darlyuk-Saadon, Rabner, Glaser, Aronheim: "Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins." in: The Journal of biological chemistry, Vol. 288, Issue 10, pp. 7294-304, (2013) (PubMed).

Lee, Komano, Saitoh, Yamaoka, Kozaki, Misawa, Takahama, Satoh, Takeuchi, Yamamoto, Matsuura, Saitoh, Akira: "Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 30, pp. 12379-84, (2013) (PubMed).

Jakobson, Jakobson, Llano, Palgi, Arumäe: "Multiple mechanisms repress N-Bak mRNA translation in the healthy and apoptotic neurons." in: Cell death & disease, Vol. 4, pp. e777, (2013) (PubMed).

Osugi, Suzuki, Nomura, Ariumi, Shibata, Maki: "Identification of the P-body component PATL1 as a novel ALG-2-interacting protein by in silico and far-Western screening of proline-rich proteins." in: Journal of biochemistry, Vol. 151, Issue 6, pp. 657-66, (2012) (PubMed).

Kobayashi, Winslow, Sunesson, Hellman, Larsson: "PKC? binds G3BP2 and regulates stress granule formation following cellular stress." in: PLoS ONE, Vol. 7, Issue 4, pp. e35820, (2012) (PubMed).

Thomas, Luchelli, Pascual, Gottifredi, Boccaccio: "A monoclonal antibody against p53 cross-reacts with processing bodies." in: PLoS ONE, Vol. 7, Issue 5, pp. e36447, (2012) (PubMed).

Li, Chen, Zhou, Xu, Li, Wang, Mao, Zhang, He, Shu: "LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 29, pp. 11770-5, (2012) (PubMed).

Target Details for DCP1A

Target: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Alternative Name: DCP1A (DCP1A Products)

Synonyms: DCP1A antibody, 1110066A22Rik antibody, 4930568L04Rik antibody, AU019772 antibody, D14Ertd817e antibody, Mitc1 antibody, SMIF antibody, RGD1561298 antibody, mitc1 antibody, HSA275986 antibody, Nbla00360 antibody, SMAD4IP1 antibody, smad4ip1 antibody, smif antibody, decapping mRNA 1A antibody, decapping mRNA 1A L homeolog antibody, DCP1A antibody, Dcp1a antibody, dcp1a antibody, dcp1a.L antibody

Background: Full Gene Name: DCP1 decapping enzyme homolog A (S. cerevisiae)
Synonyms: FLJ21691,HSA275986,Nbla00360,SMAD4IP1,SMIF

Gene ID: 55802

NCBI Accession: NM_018403