CXCL10 antibody (AA 35-98)

Catalog No. ABIN687442

Product Details anti-CXCL10 Antibody

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Binding Specificity: AA 35-98

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL10 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL10

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL10 antibody (ABIN687442)

Henschel, Cabrera, Kaldunski, Jia, Geoffrey, Roethle, Lam, Chen, Wang, Salzman, Hessner: "Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility." in: PLoS ONE, Vol. 13, Issue 1, pp. e0190351, (2018) (PubMed).

Lee, Cho, Cho, Bae, Kim, Park: "Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation." in: Laboratory animal research, Vol. 34, Issue 1, pp. 1-10, (2018) (PubMed).

Li, Nishikawa, Kaneda: "Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation." in: Scientific reports, Vol. 6, pp. 25077, (2016) (PubMed).

Iversen, Reinert, Thomsen, Bagdonaite, Nandakumar, Cheshenko, Prabakaran, Vakhrushev, Krzyzowska, Kratholm, Ruiz-Perez, Petersen, Goriely, Bibby, Eriksson, Ruland, Thomsen, Herold, Wandall, Frische et al.: "An innate antiviral pathway acting before interferons at epithelial surfaces. ..." in: Nature immunology, Vol. 17, Issue 2, pp. 150-8, (2016) (PubMed).

Clancy-Thompson, Perekslis, Croteau, Alexander, Chabanet, Turk, Huang, Mullins: "Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease." in: Cancer immunology research, Vol. 3, Issue 8, pp. 956-67, (2015) (PubMed).

Target Details for CXCL10

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Alternative Name: CXCL10 (CXCL10 Products)

Synonyms: CXCL10 antibody, C7 antibody, IFI10 antibody, INP10 antibody, IP-10 antibody, SCYB10 antibody, crg-2 antibody, gIP-10 antibody, mob-1 antibody, CRG-2 antibody, IP10 antibody, Ifi10 antibody, Scyb10 antibody, C-X-C motif chemokine ligand 10 antibody, C-X-C motif chemokine 10 antibody, chemokine (C-X-C motif) ligand 10 antibody, CXCL10 antibody, cxl10 antibody, Cxcl10 antibody

Background:

Synonyms: C7, IP10, CRG-2, INP1, IP-10, Ifi1, mob-1, Scyb1, gIP-1, C-X-C motif chemokine 1, 1 kDa interferon gamma-induced protein, Gamma-IP1, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B1, Cxcl1, Crg2

Background: In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Gene ID: 15945

UniProt: P17515