Fatty Acid Synthase antibody (AA 651-750)

Catalog No. ABIN687382

Product Details anti-Fatty Acid Synthase Antibody

Target: Fatty Acid Synthase (FASN)

Binding Specificity: AA 651-750

Reactivity: Human, Mouse, Rat, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Goat, Human, Mouse, Rat

Predicted Reactivity: Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse FASN

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Fatty Acid Synthase antibody (ABIN687382)

Yu, Zhao, Lai, Chu, Hao, Feng, Zhang, Liu, Cheng, Li, Shen, Min: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).

Li, Ye, Wang, Li, Qiang, Yu, Tang, Liu: "Effect of Octreotide on Hepatic Steatosis in Diet-Induced Obesity in Rats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0152085, (2016) (PubMed).

He, Guo, Qian, Zhang, Ren, Liu: "Synergistic hepatotoxicity by cadmium and chlorpyrifos: disordered hepatic lipid homeostasis." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 303-8, (2015) (PubMed).

Chen, Luo, Ma, Wang, Cao, Xu, Zhu, Sun, Li, Yao, Kang, Gou: "MiR130b-Regulation of PPARγ Coactivator- 1α Suppresses Fat Metabolism in Goat Mammary Epithelial Cells." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142809, (2015) (PubMed).

Zhu, Luo, Wang, Yu, Wang, Shi, Sun, Lin, Li: "Inhibition of FASN reduces the synthesis of medium-chain fatty acids in goat mammary gland." in: Animal : an international journal of animal bioscience, Vol. 8, Issue 9, pp. 1469-78, (2014) (PubMed).

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN/Fatty Acid Synthase (FASN Products)

Background:

Synonyms: FAS, A630082H08Rik, Fatty acid synthase, Fasn

Background: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Gene ID: 14104

UniProt: P19096

Pathways: AMPK Signaling