RHOC antibody (AA 101-193)

Catalog No. ABIN687157

Product Details anti-RHOC Antibody

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Binding Specificity: AA 101-193

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rho C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-RHOC antibody (ABIN687157)

He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, (2017) (PubMed).

Target Details for RHOC

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Alternative Name: Rho C (RHOC Products)

Synonyms: ARHC antibody, LOC100221682 antibody, ARH9 antibody, H9 antibody, RHOH9 antibody, AI324259 antibody, Arh9 antibody, Arhc antibody, CRHOC antibody, ras homolog family member C L homeolog antibody, ras homolog family member C antibody, rhoc.L antibody, RHOC antibody, rhoc antibody, Rhoc antibody

Background:

Synonyms: H9, ARH9, ARHC, RHOH9, Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, RHOC

Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.

Gene ID: 389

UniProt: P08134

Pathways: WNT Signaling, Cell-Cell Junction Organization