PTAFR antibody (AA 231-342)

Catalog No. ABIN687127

Product Details anti-PTAFR Antibody

Target: PTAFR (Platelet-Activating Factor Receptor (PTAFR))

Binding Specificity: AA 231-342

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTAFR antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAFR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTAFR antibody (ABIN687127)

Hammond, Lu, Gelbard: "Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation." in: Frontiers in cellular neuroscience, Vol. 9, pp. 505, (2016) (PubMed).

Target Details for PTAFR

Target: PTAFR (Platelet-Activating Factor Receptor (PTAFR))

Alternative Name: PAFR (PTAFR Products)

Synonyms: PAFR antibody, MGC52896 antibody, MGC160177 antibody, PAFr antibody, pafr antibody, PAF-R antibody, platelet activating factor receptor antibody, platelet-activating factor receptor antibody, platelet activating factor receptor L homeolog antibody, PTAFR antibody, Ptafr antibody, ptafr.L antibody, ptafr antibody

Background:

Synonyms: PAFR, Platelet-activating factor receptor, PAF-R, PTAFR

Background: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

Gene ID: 5724

UniProt: P25105

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin