LIFR antibody (AA 451-580)

Catalog No. ABIN686827

Product Details anti-LIFR Antibody

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Binding Specificity: AA 451-580

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat LIFR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LIFR antibody (ABIN686827)

Murphy, Halow, Royer, Hennebold: "Leukemia Inhibitory Factor Is Necessary for Ovulation in Female Rhesus Macaques." in: Endocrinology, Vol. 157, Issue 11, pp. 4378-4387, (2016) (PubMed).

Target Details for LIFR

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Alternative Name: Lifr/Cd118 (LIFR Products)

Synonyms: A230075M04Rik antibody, AW061234 antibody, LIF antibody, CD118 antibody, LIF-R antibody, SJS2 antibody, STWS antibody, SWS antibody, leukemia inhibitory factor receptor antibody, LIF receptor alpha antibody, leukemia inhibitory factor receptor alpha antibody, Lifr antibody, LOC397451 antibody, LIFR antibody

Background:

Synonyms: SWS, SJS2, STWS, CD118, LIF-R, Leukemia inhibitory factor receptor, LIF receptor, LIFR

Background: Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Gene ID: 3977

UniProt: O70535

Pathways: JAK-STAT Signaling, Growth Factor Binding